Ontology highlight
ABSTRACT:
SUBMITTER: Benoit MPMH
PROVIDER: S-EPMC5916938 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Benoit Matthieu P M H MPMH Asenjo Ana B AB Sosa Hernando H
Nature communications 20180425 1
Kinesin-13s constitute a distinct group within the kinesin superfamily of motor proteins that promote microtubule depolymerization and lack motile activity. The molecular mechanism by which kinesin-13s depolymerize microtubules and are adapted to perform a seemingly very different activity from other kinesins is still unclear. To address this issue, here we report the near atomic resolution cryo-electron microscopy (cryo-EM) structures of Drosophila melanogaster kinesin-13 KLP10A protein constru ...[more]