Dataset Information

ABC Dementia Scale: A Quick Assessment Tool for Determining Alzheimer's Disease Severity.

ABSTRACT:

Background

In this study, we examined the construct validity, concurrent validity concerning other standard scales, intrarater reliability, and changes in scores at 12 weeks of the previously developed ABC Dementia Scale (ABC-DS), a novel assessment tool for Alzheimer's disease (AD).

Methods

Data were obtained from 312 patients diagnosed with either AD or mild cognitive impairment. The scores on the ABC-DS and standard scales were compared.

Results

The 13 items of the ABC-DS are grouped into three domains, and the domain-level scores were highly correlated with the corresponding conventional scales. Statistically significant changes in assessment scores after 12 weeks were observed for the total ABC-DS scores.

Conclusion

Our results demonstrate the ABC-DS to have good validity and reliability, and its usefulness in busy clinical settings.

SUBMITTER: Mori T

PROVIDER: S-EPMC5921188 | biostudies-literature | 2018 Jan-Apr

REPOSITORIES: biostudies-literature

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Publications

ABC Dementia Scale: A Quick Assessment Tool for Determining Alzheimer's Disease Severity.

Mori Takahiro T Kikuchi Takashi T Umeda-Kameyama Yumi Y Wada-Isoe Kenji K Kojima Shinsuke S Kagimura Tatsuo T Kudoh Chiaki C Uchikado Hirotake H Ueki Akinori A Yamashita Masato M Watabe Toshiyuki T Nishimura Chika C Tsuno Norifumi N Ueda Takashi T Akishita Masahiro M Nakamura Yu Y

Dementia and geriatric cognitive disorders extra 20180101 1

<h4>Background</h4>In this study, we examined the construct validity, concurrent validity concerning other standard scales, intrarater reliability, and changes in scores at 12 weeks of the previously developed ABC Dementia Scale (ABC-DS), a novel assessment tool for Alzheimer's disease (AD).<h4>Methods</h4>Data were obtained from 312 patients diagnosed with either AD or mild cognitive impairment. The scores on the ABC-DS and standard scales were compared.<h4>Results</h4>The 13 items of the ABC-D ...[more]

PMID: 29706985

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Project description:Cognitive screening is often a first step to document cognitive status of patients suspected having Alzheimer's disease (AD). Unfortunately, screening neuropsychological tests are often insensitivity in the detection. The goal of this study was to develop a simple and sensitive screening neuropsychological test to facilitate early detection of AD. This study recruited 761 elderly individuals suspected of having AD and presenting various cognitive statuses (mean age: 77.69 ± 8.45 years; proportion of females: 65%; cognitively unimpaired, CU, n = 133; mild cognitive impairment, MCI, n = 231; dementia of Alzheimer's type, DAT, n = 397). This study developed a novel screening neuropsychological test incorporating assessments of the core memory deficits typical of early AD and an interview on memory function with an informant. The proposed History-based Artificial Intelligence-Show Chwan Assessment of Cognition (HAI-SAC) was assessed in terms of psychometric properties, test time, and discriminative ability. The results were compared with those obtained using other common screening tests, including Cognitive Abilities Screening Instrument (CASI), Montreal Cognitive Assessment (MoCA), and an extracted Mini-Mental State Examination score from CASI. HAI-SAC demonstrated acceptable internal consistency. Factor analysis revealed two factors: memory (semantic and contextual) and cognition-related information from informants. The assessment performance of HAI-SAC was strongly correlated with that of the common screening neuropsychological tests addressed in this study. HAI-SAC outperformed the other tests in differentiating CU individuals from patients with MCI (sensitivity: 0.87; specificity: 0.58; area under the curve [AUC]: 0.78) or DAT (sensitivity: 0.99; specificity: 0.89; AUC: 0.98). Performance of HAI-SAC on differentiating MCI from DAT was on par with performances of other tests (sensitivity: 0.78; specificity: 0.84; AUC: 0.87), while the test time was less than one quarter that of CASI and half that of MoCA. HAI-SAC is psychometrically sound, cost-effective, and sensitive in discriminating the cognitive status of AD.

Dataset Information

ABC Dementia Scale: A Quick Assessment Tool for Determining Alzheimer's Disease Severity.

Background

Methods

Results

Conclusion

Publications

ABC Dementia Scale: A Quick Assessment Tool for Determining Alzheimer's Disease Severity.

Similar Datasets

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