Ontology highlight
ABSTRACT:
SUBMITTER: Ma D
PROVIDER: S-EPMC5923270 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Ma David D Wang Amy C AC Parikh Ishita I Green Stefan J SJ Hoffman Jared D JD Chlipala George G Murphy M Paul MP Sokola Brent S BS Bauer Björn B Hartz Anika M S AMS Lin Ai-Ling AL
Scientific reports 20180427 1
Neurovascular integrity, including cerebral blood flow (CBF) and blood-brain barrier (BBB) function, plays a major role in determining cognitive capability. Recent studies suggest that neurovascular integrity could be regulated by the gut microbiome. The purpose of the study was to identify if ketogenic diet (KD) intervention would alter gut microbiome and enhance neurovascular functions, and thus reduce risk for neurodegeneration in young healthy mice (12-14 weeks old). Here we show that with 1 ...[more]