Ontology highlight
ABSTRACT:
SUBMITTER: de Oliveira LC
PROVIDER: S-EPMC5923434 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
de Oliveira Leonardo C LC Brasil Bruno S A F BSAF Unger Bethany B Trindade Giliane S GS Abrahão Jonatas S JS Kroon Erna G EG Traktman Paula P Bonjardim Cláudio A CA
Viruses 20180321 4
Evolution has equipped poxvirus genomes with the coding capacity for several virus-host interaction products which interfere with host cell gene expression and protein function, creating an adequate intracellular environment for a productive infection. We show here that <i>Vaccinia virus</i> (VACV) induces the expression of the cellular transcription factor EGR-1 (early growth response-1) in Mouse Embryonic Fibroblasts (MEFs) through the MEK (mitogen-activated protein kinase (MAPK)/ERK)/ERK (ext ...[more]