Ontology highlight
ABSTRACT:
SUBMITTER: Chang JE
PROVIDER: S-EPMC5923897 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Chang Julie E JE Havighurst Thomas T Kim KyungMann K Eickhoff Jens J Traynor Anne M AM Kirby-Slimp Rachel R Volk Lynn M LM Werndli Jae J Go Ronald S RS Weiss Matthias M Blank Jules J Kahl Brad S BS
British journal of haematology 20160223 2
Bendamustine + rituximab (BR) has demonstrated high response rates in relapsed/refractory (R/R) chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL). However, progression-free survival (PFS) after BR is <18 months. This study was designed to determine if maintenance lenalidomide after BR induction could improve PFS in R/R CLL/SLL. Thirty-four patients with R/R CLL/SLL who had received 1-5 prior chemotherapy regimens were treated with 6 cycles of BR induction. Patients achievi ...[more]