Dataset Information

Intravoxel incoherent motion (IVIM) and non-Gaussian diffusion MRI of the lactating breast.

ABSTRACT: Purpose:To investigate the effect of breastfeeding on IVIM and non-Gaussian diffusion MRI in the breast. Materials and methods:An IRB approved prospective study enrolled seventeen volunteers (12 in lactation and 5 with post-weaning, range 31-43?years; mean 35.4?years). IVIM (fIVIM and D*) and non-Gaussian diffusion (ADC0 and K) parameters using 16 b values, plus synthetic apparent diffusion coefficients (sADCs) from 2 key b values (b?=?200 and 1500?s/mm2) were calculated using regions of interest. ADC0 maps of the whole breast were generated and their contrast patterns were evaluated by two independent readers using retroareolar and segmental semi-quantitative scores. To compare the diffusion and IVIM parameters, Wilcoxon signed rank tests were used between pre- and post-breastfeeding and Mann-Whitney tests were used between post-weaning and pre- or post-breastfeeding. Results:ADC0 and sADC values significantly decreased post-breastfeeding (1.90 vs. 1.72?×?10-3?mm2/s, P?

SUBMITTER: Iima M

PROVIDER: S-EPMC5926247 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Intravoxel incoherent motion (IVIM) and non-Gaussian diffusion MRI of the lactating breast.

Iima Mami M Kataoka Masako M Sakaguchi Rena R Kanao Shotaro S Onishi Natsuko N Kawai Makiko M Ohashi Akane A Murata Katsutoshi K Togashi Kaori K

European journal of radiology open 20180202

<h4>Purpose</h4>To investigate the effect of breastfeeding on IVIM and non-Gaussian diffusion MRI in the breast.<h4>Materials and methods</h4>An IRB approved prospective study enrolled seventeen volunteers (12 in lactation and 5 with post-weaning, range 31-43 years; mean 35.4 years). IVIM (f<sub>IVIM</sub> and D*) and non-Gaussian diffusion (ADC<sub>0</sub> and K) parameters using 16 b values, plus synthetic apparent diffusion coefficients (sADCs) from 2 key b values (b = 200 and 1500 s/mm<sup>2 ...[more]

PMID: 29719854

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Dataset Information

Intravoxel incoherent motion (IVIM) and non-Gaussian diffusion MRI of the lactating breast.

Publications

Intravoxel incoherent motion (IVIM) and non-Gaussian diffusion MRI of the lactating breast.

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