Browse
Submit Data
Databases
API
Help

Dataset Information

23 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Variations in Social Network Type Membership Among Older African Americans, Caribbean Blacks, and Non-Hispanic Whites.

ABSTRACT:

Objectives

This study examined race differences in the probability of belonging to a specific social network typology of family, friends, and church members.

Method

Samples of African Americans, Caribbean blacks, and non-Hispanic whites aged 55+ were drawn from the National Survey of American Life. Typology indicators related to social integration and negative interactions with family, friendship, and church networks were used. Latent class analysis was used to identify typologies, and latent class multinomial logistic regression was used to assess the influence of race, and interactions between race and age, and race and education on typology membership.

Results

Four network typologies were identified: optimal (high social integration, low negative interaction), family-centered (high social integration within primarily the extended family network, low negative interaction), strained (low social integration, high negative interaction), and ambivalent (high social integration and high negative interaction). Findings for race and age and race and education interactions indicated that the effects of education and age on typology membership varied by race.

Discussion

Overall, the findings demonstrate how race interacts with age and education to influence the probability of belonging to particular network types. A better understanding of the influence of race, education, and age on social network typologies will inform future research and theoretical developments in this area.

SUBMITTER: Nguyen AW

PROVIDER: S-EPMC5927094 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Biomarkers associated with pulse pressure in African-Americans and non-Hispanic whites.

Project description:Pulse pressure (an indirect measure of arterial stiffness) is a robust predictor of cardiovascular events, but its pathophysiology remains poorly understood. To gain insight into the pathophysiology of arterial stiffness we conducted an exploratory investigation of the associations of 47 circulating biomarkers in etiologic pathways of arteriosclerosis with brachial artery pulse pressure.Participants included 1,193 African-Americans and 1,145 non-Hispanic whites belonging to hypertensive sibships. Blood pressure (BP) was measured with a random-zero sphygmomanometer. Multivariable linear regression was employed to assess the associations of biomarkers with pulse pressure after adjustment for age, sex, conventional risk factors, mean arterial pressure, heart rate, and use of aspirin, statins, estrogens, and antihypertensives. Statistical significance was set at P ? 0.001 (Bonferroni correction for multiple testing).Log N-terminal probrain natriuretic peptide (NT-proBNP) (African-Americans: ? = 2.11 ± 0.52, non-Hispanic whites: ? = 2.65 ± 0.55), log midregional proatrial natriuretic peptide (African-Americans: ? = 4.83 ± 0.70, non-Hispanic whites: ? = 3.70 ± 0.67), and log osteoprotegerin (African-Americans: ? = 4.64 ± 1.02, non-Hispanic whites: ? = 4.19 ± 0.99) were independently associated with pulse pressure (P < 0.001 for all) in both ethnicities. Log C-reactive protein (CRP) (? = 1.56 ± 0.35), log midregional proadrenomedullin (MR-proADM) (? = 5.53 ± 1.19) and log matrix metalloproteinase-2 (? = 3.89 ± 1.06) were associated with greater pulse pressure in African-Americans only (P ? 0.001 for all), whereas higher fibrinogen was associated with pulse pressure in non-Hispanic whites only (? = 0.02 ± 0.004. P < 0.001).Our results suggest that hemodynamic stress, vascular inflammation and calcification, and matrix remodeling may have a role in the pathogenesis and/or adverse consequences of increased pulse pressure.

| S-EPMC3707798 | biostudies-literature

Human Hippocampus from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3

Project description:This study examined global proteomic changes in postmortem hippocampus tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using Tandem Mass Tags (TMT)10plex.

2020-10-19 | PXD012114 | Pride

Human Globus Pallidus (GP) from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3

Project description:This study examined global proteomic changes in postmortem globus pallidus (GP) tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using Tandem Mass Tags (TMT)10plex.

2020-10-19 | PXD014371 | Pride

Effects of early-life adversity on cognitive decline in older African Americans and whites.

Project description:ObjectivesEarly-life adversity is related to adult health in old age but little is known about its relation with cognitive decline.MethodsParticipants included more than 6,100 older residents (mean age = 74.9 [7.1] years; 61.8% African American) enrolled in the Chicago Health and Aging Project, a geographically defined, population-based study of risk factors for Alzheimer disease. Participants were interviewed at approximately 3-year intervals for up to 16 years. The interview included a baseline evaluation of early-life adversity, and administration of 4 brief cognitive function tests to assess change in cognitive function. We estimated the relation of early-life adversity to rate of cognitive decline in a series of mixed-effects models.ResultsIn models stratified by race, and adjusted for age and sex, early-life adversity was differentially related to decline in African Americans and whites. Whereas no measure of early-life adversity related to cognitive decline in whites, both food deprivation and being thinner than average in early life were associated with a slower rate of cognitive decline in African Americans. The relations were not mediated by years of education and persisted after adjustment for cardiovascular factors.ConclusionsMarkers of early-life adversity had an unexpected protective effect on cognitive decline in African Americans.

| S-EPMC3578376 | biostudies-literature

Professional Service Use for a Serious Personal Problem: Comparing Older African Americans, Black Caribbeans, and Non-Hispanic Whites Using the National Survey of American Life.

Project description:Examines combinations of professionals visited for a serious personal problem.The sample includes those aged 55 and above (N = 862) from the National Survey of American Life (NSAL). Latent class analysis was used to identify groups of respondents based on types of professionals visited. Multinomial logistic regression was used to identify factors associated with group membership.Classes included health provider plus clergy, physician plus mental health provider, and limited provider use. Whites were more likely than African Americans to fall into the health provider plus clergy and physician plus mental health provider classes. Those with physical and emotional problems were more likely to be in the health provider plus clergy and physician plus mental health provider classes, respectively.Most respondents were in the limited provider use class suggesting that for many problems, minimal professional help is utilized. Physicians and clergy were important across all three classes.

| S-EPMC4486639 | biostudies-literature

Human Inferior Parietal Lobule (IPL) from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3

Project description:This study examined global proteomic changes in postmortem inferior parietal lobule (IPL) tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using Tandem Mass Tags (TMT)11plex.

2020-10-19 | PXD014372 | Pride

Food acculturation drives dietary differences among Mexicans, Mexican Americans, and Non-Hispanic Whites.

Project description:Our aim was to examine the effects of food acculturation on Mexican Americans' (MA) diets, taking the Mexican diet as reference. We used nationally representative samples of children (2-11 y) and female adolescents and adults (12-49 y) from the Mexican National Nutrition Survey 1999 and NHANES 1999-2006 to compare the diets of Mexicans (n = 5678), MA born in Mexico (MAMX) (n = 1488), MA born in the United States (MAUS) (n = 3654), and non-Hispanic white Americans (NH-White) (n = 5473). One 24-h diet recall was used to examine the percentage consuming and percentage energy consumed from selected food groups. Most of the food groups analyzed displayed a fairly linear increase or decrease in percent energy/capita intake in this order: Mexican, MAMX, MAUS, NH-White. However, few significant differences were observed among the US subpopulations, especially among MAUS and NH-Whites. Overall, compared to Mexicans, the US subpopulations had greater intakes of saturated fat, sugar, dessert and salty snacks, pizza and French fries, low-fat meat and fish, high-fiber bread, and low-fat milk, as well as decreased intakes of corn tortillas, low-fiber bread, high-fat milk, and Mexican fast food. Furthermore, the patterns were similar in all age groups. Although we found a mix of positive and negative aspects of food acculturation, the overall proportion of energy obtained from unhealthy foods was higher among the US subpopulations. Our findings indicate that within one generation in the US, the influence of the Mexican diet is almost lost. In addition, our results reinforce the need to discourage critical unhealthful components of the American diet among MA.

| S-EPMC3174859 | biostudies-other

Normative Data for the Symbol Digit Modalities Test in Older White Australians and Americans, African-Americans, and Hispanic/Latinos.

Project description:Background:Processing speed, which can be assessed using the Symbol Digit Modalities Test (SDMT), is central to many brain functions. Processing speed declines with advanced age but substantial impairments are indicative of brain injury or disease. Objective:The purpose of this study was to provide SDMT normative data for older community-dwelling individuals in the U.S. and Australia. Methods:The ASPREE trial recruited 19,114 relatively healthy older men and women in Australia and the U.S. from the general community. All participants were without a diagnosis of dementia and with a Modified Mini-Mental State examination score of 78 or more at enrolment. The SDMT was administered at baseline as part of a neuropsychological test battery. Results:The median age of participants was 74 years (range 65-99), and 56% were women. The median years of education was 12. Ethno-racial differences in SDMT performance were observed and normative data were thus presented separately for 16,289 white Australians, 1,082 white Americans, 891 African-Americans, and 316 Hispanic/Latinos. There were consistent positive associations found between SDMT and education level, and negative associations between SDMT and age. Mean scores for women were consistently higher than men with the exception of Hispanic/Latinos aged ?70 years. Conclusion:This study provides comprehensive SDMT normative data for whites (Australian and U.S.), Hispanic/Latinos, and African-Americans, according to gender, age, and education level. These norms can be used clinically as reference standards to screen for cognitive impairments in older individuals.

| S-EPMC7504980 | biostudies-literature

Differences in subcutaneous adipose tissue gene expression between obese African Americans and Hispanic Youths

Project description:Obesity is a major risk factor for several chronic diseases including diabetes, fatty liver disease and cancer. Despite similar propensities for obesity, Hispanics and African Americans exhibit unique and distinct differences in obesity related outcomes such as greater risk of, obesity-related cancers in AA and non alcoholic fatty liver disease (NAFLD) in Hispanics. This study was aimed to determine whether differences in subcutaneous adipose tissue (SAT) gene expression in obese, Hispanic and AA young adults might explain ethnic differences in obesity-related phenotypes.

2011-08-01 | GSE23506 | GEO

The role of education on Cancer amenable mortality among non-Hispanic blacks & non-Hispanic whites in the United States (1989-2018).

Project description:BackgroundCancer mortality in the U.S. has fallen in recent decades; however, individuals with lower levels of education experienced a smaller decline than more highly educated individuals. This analysis aimed to measure the influence of education lower than a high school diploma, on cancer amenable mortality among Non-Hispanic Whites (NHW) and Non-Hispanic Blacks (NHB) in the U.S. from 1989 to 2018.MethodsWe analyzed data from 8.2 million death certificates of men and women who died from cancer between 1989 and 2018. We examined 5-year and calendar period intervals, as well as annual percent changes (APC). APC was adjusted for each combination of sex, educational level, and race categories (8 models) to separate the general trend from the effects of age.ResultsOur study demonstrated an increasing mortality gap between the least and the most educated NHW and NHB males and females who died from all cancers combined and for most other cancer types included in this study. The gap between the least and the most educated was broader among NHW males and females than among NHB males and females, respectively, for most malignancies.ConclusionsIn summary, we reported an increasing gap in the age-adjusted cancer mortality among the most and the least educated NHW and NHB between 25 and 74 years of age. We demonstrated that although NHB exhibited the greatest age-adjusted mortality rates for most cancer locations, the gap between the most and the least educated was shown for NHW.

| S-EPMC8425171 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data