Ontology highlight
ABSTRACT:
SUBMITTER: Kaczmarek R
PROVIDER: S-EPMC5927444 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Kaczmarek Radoslaw R Szymczak-Kulus Katarzyna K Bereźnicka Anna A Mikołajczyk Krzysztof K Duk Maria M Majorczyk Edyta E Krop-Watorek Anna A Klausa Elżbieta E Skowrońska Joanna J Michalewska Bogumiła B Brojer Ewa E Czerwinski Marcin M
PloS one 20180430 4
Contrary to the mainstream blood group systems, P1PK continues to puzzle and generate controversies over its molecular background. The P1PK system comprises three glycosphingolipid antigens: Pk, P1 and NOR, all synthesised by a glycosyltransferase called Gb3/CD77 synthase. The Pk antigen is present in most individuals, whereas P1 frequency is lesser and varies regionally, thus underlying two common phenotypes: P1, if the P1 antigen is present, and P2, when P1 is absent. Null and NOR phenotypes a ...[more]