Multivariable clinical-genetic risk model for predicting venous thromboembolic events in patients with cancer.

ABSTRACT:

Background

Venous thromboembolism (VTE) is a leading cause of death among patients with cancer. Outpatients with cancer should be periodically assessed for VTE risk, for which the Khorana score is commonly recommended. However, it has been questioned whether this tool is sufficiently accurate at identifying patients who should receive thromboprophylaxis. The present work proposes a new index, TiC-Onco risk score to be calculated at the time of diagnosis of cancer, that examines patients' clinical and genetic risk factors for thrombosis.

Methods

We included 391 outpatients with a recent diagnosis of cancer and candidates for systemic outpatient chemotherapy. All were treated according to standard guidelines. The study population was monitored for 6 months, and VTEs were recor

SUBMITTER: Munoz Martin AJ 

PROVIDER: S-EPMC5931103 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature