Ontology highlight
ABSTRACT:
SUBMITTER: Morici JF
PROVIDER: S-EPMC5931799 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
eLife 20180502
Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues. When the cue is presented, the most relevant memory should be updated. In a contextual version of the object recognition task, we examined the effect of medial PFC (mPFC) serotonin 2a receptor (5-HT2aR) blockade during retrieval in reconsolidation of competing objects memories. We found that mPFC 5 ...[more]