Ontology highlight
ABSTRACT:
SUBMITTER: Zhu C
PROVIDER: S-EPMC5932055 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Zhu Chen C Xia Lixia L Li Fei F Zhou Lingren L Weng Qingyu Q Li Zhouyang Z Wu Yinfang Y Mao Yuanyuan Y Zhang Chao C Wu Yanping Y Li Miao M Ying Songmin S Chen Zhihua Z Shen Huahao H Li Wen W
Scientific reports 20180502 1
Eosinophil infiltration is considered a hallmark in allergic airway inflammation, and the blockade of eosinophil differentiation may be an effective approach for treating eosinophil-related disorders. Mammalian target of rapamycin (mTOR) is a vital modulator in cell growth control and related diseases, and we have recently demonstrated that rapamycin can suppress eosinophil differentiation in allergic airway inflammation. Considering its critical role in haematopoiesis, we further investigated t ...[more]