Ontology highlight
ABSTRACT:
SUBMITTER: Fletcher NM
PROVIDER: S-EPMC5933080 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Fletcher Nicole M NM Saed Mohammed G MG Abuanzeh Suleiman S Abu-Soud Husam M HM Al-Hendy Ayman A Diamond Michael P MP Saed Ghassan M GM
Reproductive sciences (Thousand Oaks, Calif.) 20140211 9
Uterine fibroids are the most common benign tumor in women. The goal of this study was to investigate whether nicotinamide adenine dinucleotide phosphate oxidase (NOX), a major source of superoxide and subsequent oxidative stress, was differentially regulated in myometrium versus leiomyoma. Expression levels of NOXs1-5, dual oxidase (DUOX), DUOX2, NOX organizer (NOXO) 1, NOX activator 1, p47(phox), p67(phox), and p22(phox) were determined in cells treated with hypoxia by real-time reverse transc ...[more]