Dataset Information

Modifiable risk factors associated with bronchiolitis.

ABSTRACT:

Background

We sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants.

Methods

For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases: median age: 2 months; age range: 0.5-12 months; boys: 55.4%) and 213 children aged <3 years (controls: median age: 12 months; age range: 0.5-36 months; boys: 54.5%) with a negative medical history for lower respiratory tract diseases hospitalized at 'Sapienza' University Rome and IRCCS Bambino Gesù Hospital. Infants' parents completed a standardized 53-item questionnaire seeking information on social-demographic and clinical characteristics, indoor pollution, eating habits and outdoor air pollution. Multivariate logistic regression analyses were run to assess the independent effect of risk factors, accounting for confounders and effect modifiers.

Results

In the 213 hospitalized infants the questionnaire identified the following risk factors for acute bronchiolitis: breastfeeding ?3 months (OR: 2.1, 95% confidence interval [CI]: 1.2-3.6), presence of older siblings (OR: 2.8, 95% CI: 1.7-4.7), ?4 cohabitants (OR: 1.5, 95% CI: 1.1-2.1), and using seed oil for cooking (OR: 1.7, 95% CI: 1.2-2.6). Having renovated their home in the past 12 months and concurrently being exposed daily to smoking, involving more than 11 cigarettes and two or more smoking cohabitants, were more frequent factors in cases than in controls ( p = 0.021 and 0.05), whereas self-estimated proximity to road and traffic was similar in the two groups.

Conclusions

We identified several risk factors for acute bronchiolitis related to indoor and outdoor pollution, including inhaling cooking oil fumes. Having this information would help public health authorities draw up effective preventive measures - for example, teach mothers to avoid handling their child when they have a cold and eliminate exposure to second-hand tobacco smoke.

SUBMITTER: Nenna R

PROVIDER: S-EPMC5933664 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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Publications

Modifiable risk factors associated with bronchiolitis.

Nenna Raffaella R Cutrera Renato R Frassanito Antonella A Alessandroni Claudia C Nicolai Ambra A Cangiano Giulia G Petrarca Laura L Arima Serena S Caggiano Serena S Ullmann Nicola N Papoff Paola P Bonci Enea E Moretti Corrado C Midulla Fabio F

Therapeutic advances in respiratory disease 20170816 10

<h4>Background</h4>We sought to clarify possibly modifiable risk factors related to pollution responsible for acute bronchiolitis in hospitalized infants.<h4>Methods</h4>For this observational study, we recruited 213 consecutive infants with bronchiolitis (cases: median age: 2 months; age range: 0.5-12 months; boys: 55.4%) and 213 children aged <3 years (controls: median age: 12 months; age range: 0.5-36 months; boys: 54.5%) with a negative medical history for lower respiratory tract diseases ho ...[more]

PMID: 28812472

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Dataset Information

Modifiable risk factors associated with bronchiolitis.

Background

Methods

Results

Conclusions

Publications

Modifiable risk factors associated with bronchiolitis.

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