Ontology highlight
ABSTRACT:
SUBMITTER: Jindal V
PROVIDER: S-EPMC5934142 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Journal of gastrointestinal oncology 20180401 2
Gastrointestinal (GIT) tumors are extremely fatal and lethal tumors with limited therapeutic options. Antitumor immunity is new line of research in management of solid tumors. Immune check points are negative regulators of immune system and control the immune response. These checkpoints are exploited by cancer cells. Cancer cells causes early activation of checkpoints and suppress the immune response, and therefore have unchecked growth and metastasis of malignant cells. Immune checkpoint inhibi ...[more]