Ontology highlight
ABSTRACT:
SUBMITTER: Lawrence MG
PROVIDER: S-EPMC5934300 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Lawrence Monica G MG Palacios-Kibler Thamiris V TV Workman Lisa J LJ Schuyler Alexander J AJ Steinke John W JW Payne Spencer C SC McGowan Emily C EC Patrie James J Fuleihan Ramsay L RL Sullivan Kathleen E KE Lugar Patricia L PL Hernandez Camellia L CL Beakes Douglas E DE Verbsky James W JW Platts-Mills Thomas A E TAE Cunningham-Rundles Charlotte C Routes John M JM Borish Larry L
Journal of clinical immunology 20180217 3
Although small prior studies have suggested that IgE can be low in common variable immunodeficiency (CVID), the workup for patients with recurrent infections and suspected hypogammaglobulinemia does not include the routine measurement of serum IgE. We sought to test the hypothesis that low/undetectable serum IgE is characteristic of CVID by comparing the frequency of low/undetectable serum IgE in healthy controls and patients with CVID. We measured total serum IgE in a large multi-center cohort ...[more]