Ontology highlight
ABSTRACT:
SUBMITTER: Clarkson YL
PROVIDER: S-EPMC5934371 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Clarkson Yvonne L YL McLaughlin Marie M Waterfall Martin M Dunlop Cheryl E CE Skehel Paul A PA Anderson Richard A RA Telfer Evelyn E EE
Scientific reports 20180503 1
The existence of a population of putative stem cells with germline developmental potential (oogonial stem cells: OSCs) in the adult mammalian ovary has been marked by controversy over isolation methodology and potential for in-vitro transformation, particularly where cell sorting has been based on expression of DEAD box polypeptide 4 (DDX4). This study describes a refined tissue dissociation/fluorescence-activated cell sorting (FACS) protocol for the ovaries of adult women which results in incre ...[more]