Ontology highlight
ABSTRACT:
SUBMITTER: Heger L
PROVIDER: S-EPMC5934495 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Heger Lukas L Balk Silke S Lühr Jennifer J JJ Heidkamp Gordon F GF Lehmann Christian H K CHK Hatscher Lukas L Purbojo Ariawan A Hartmann Arndt A Garcia-Martin Fayna F Nishimura Shin-Ichiro SI Cesnjevar Robert R Nimmerjahn Falk F Dudziak Diana D
Frontiers in immunology 20180427
Dendritic cells (DCs) are major players for the induction of immune responses. Apart from plasmacytoid DCs (pDCs), human DCs can be categorized into two types of conventional DCs: CD141<sup>+</sup> DCs (cDC1) and CD1c<sup>+</sup> DCs (cDC2). Defining uniquely expressed surface markers on human immune cells is not only important for the identification of DC subpopulations but also a prerequisite for harnessing the DC subset-specific potential in immunomodulatory approaches, such as antibody-media ...[more]