Ontology highlight
ABSTRACT:
SUBMITTER: He Q
PROVIDER: S-EPMC5934549 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
He Qin Q Fu Yu Y Tian Dean D Yan Wei W
American journal of cancer research 20180401 4
Chronic inflammation plays a decisive role at different stages of cancer development. Inflammasomes are oligomeric protein complexes activated in response to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). PAMPs and DAMPs are released from infected cells, tumors and damaged tissues. Inflammasomes activate and release inflammatory cytokines such as IL-1β and IL-18. The various inflammasomes and inflammatory cytokines and chemokines play contrasting ...[more]