Ontology highlight
ABSTRACT:
SUBMITTER: Balaguer C
PROVIDER: S-EPMC5935853 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Balaguer Catalina C Peralta Alejandro A Ríos Ángel Á Iglesias Amanda A Valera Josep Lluís JL Noguera Aina A Soriano Joan B JB Agustí Àlvar À Sala-Llinas Ernest E
Contemporary clinical trials communications 20160114
<h4>Introduction</h4>Statins may have pleiotropic effects in COPD, but mechanisms remain unclear.<h4>Objectives</h4>To assess the pleiotropic effect of statins in patients with stable COPD on (<i>1</i>): lung function (<i>2</i>); pulmonary and systemic inflammation (<i>3</i>); endothelial function (vascular stiffness) and circulating vascular growth factors; and (<i>4</i>), serum uric acid levels.<h4>Method</h4>Pilot, double-blind, randomized, placebo-controlled clinical trial in 24 patients wit ...[more]