Ontology highlight
ABSTRACT:
SUBMITTER: Jubierre L
PROVIDER: S-EPMC5938021 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Experimental & molecular medicine 20180427 4
Approximately 15,000 new cases of pediatric cancer are diagnosed yearly in Europe, with 8-10% corresponding to neuroblastoma, a rare disease with an incidence of 8-9 cases per million children <15 years of age. Although the survival rate for low-risk and intermediate-risk patients is excellent, half of children with high-risk, refractory, or relapsed tumors will be cured, and two-thirds of the other half will suffer major side effects and life-long disabilities. Epigenetic therapies aimed at rev ...[more]