Ontology highlight
ABSTRACT:
SUBMITTER: Korchak S
PROVIDER: S-EPMC5938614 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Korchak Sergey S Yang Shengjun S Mamone Salvatore S Glöggler Stefan S
ChemistryOpen 20180508 5
Diseases such as Alzheimer's and cancer have been linked to metabolic dysfunctions, and further understanding of metabolic pathways raises hope to develop cures for such diseases. To broaden the knowledge of metabolisms in vitro and in vivo, methods are desirable for direct probing of metabolic function. Here, we are introducing a pulsed nuclear magnetic resonance (NMR) approach to generate hyperpolarized metabolites within seconds, which act as metabolism probes. Hyperpolarization represents a ...[more]