HOXB9 promotes endometrial cancer progression by targeting E2F3.
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ABSTRACT:
SUBMITTER: Wan J
PROVIDER: S-EPMC5938704 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Publications
HOXB9 promotes endometrial cancer progression by targeting E2F3.
Wan Junhu J Liu Hongyang H Feng Quanling Q Liu Jun J Ming Liang L
Cell death & disease 20180501 5
HOXB9, as a HOX family transcription factor, playing a significant role in embryonic development and cancer progression. However, the function of HOXB9 and its precise mechanism in regulating endometrial cancer progression remains unknown. Here, we demonstrated that the expression of HOXB9 was increased in endometrial cancer, and associated with histological grade and lymph node metastasis. In addition, elevated HOXB9 predicts a poor prognosis in endometrial cancer patients. Interestingly, bioin ...[more]
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