Comprehensive Morpho-Electrotonic Analysis Shows 2 Distinct Classes of L2 and L3 Pyramidal Neurons in Human Temporal Cortex.
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ABSTRACT:
SUBMITTER: Deitcher Y
PROVIDER: S-EPMC5939232 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Comprehensive Morpho-Electrotonic Analysis Shows 2 Distinct Classes of L2 and L3 Pyramidal Neurons in Human Temporal Cortex.
Deitcher Yair Y Eyal Guy G Kanari Lida L Verhoog Matthijs B MB Atenekeng Kahou Guy Antoine GA Mansvelder Huibert D HD de Kock Christiaan P J CPJ Segev Idan I
Cerebral cortex (New York, N.Y. : 1991) 20171101 11
There have been few quantitative characterizations of the morphological, biophysical, and cable properties of neurons in the human neocortex. We employed feature-based statistical methods on a rare data set of 60 3D reconstructed pyramidal neurons from L2 and L3 in the human temporal cortex (HL2/L3 PCs) removed after brain surgery. Of these cells, 25 neurons were also characterized physiologically. Thirty-two morphological features were analyzed (e.g., dendritic surface area, 36 333 ± 18 157 μm2 ...[more]
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