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Natural History of Hepatitis C.


ABSTRACT: Hepatitis C infection is a common cause of cirrhosis and indication for liver transplantation in the United States. The incidence of chronic hepatitis C has been declining, but rates of cirrhosis and hepatocellular carcinoma are projected to increase. The outcome of chronic hepatitis C is variable. It is estimated that 20% to 25% will develop cirrhosis over a 25-year to 30-year period. The rate of disease progression is influenced by many host, viral, and environmental factors. Few can be modified.

SUBMITTER: Lingala S 

PROVIDER: S-EPMC5939344 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Natural History of Hepatitis C.

Lingala Shilpa S   Ghany Marc G MG  

Gastroenterology clinics of North America 20150825 4


Hepatitis C infection is a common cause of cirrhosis and indication for liver transplantation in the United States. The incidence of chronic hepatitis C has been declining, but rates of cirrhosis and hepatocellular carcinoma are projected to increase. The outcome of chronic hepatitis C is variable. It is estimated that 20% to 25% will develop cirrhosis over a 25-year to 30-year period. The rate of disease progression is influenced by many host, viral, and environmental factors. Few can be modifi  ...[more]

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