Feasibility of magnetoencephalographic source imaging in patients with thalamic deep brain stimulation for epilepsy.

ABSTRACT: Source localization of interictal spikes in patients with medically refractory epilepsy is the most common clinical application of magnetoencephalography (MEG). In recent decades, many patients with intractable epilepsy have been treated with various forms of neurostimulation, including thalamic deep brain stimulation (DBS). Patients with suboptimal seizure control after DBS might in some cases benefit from further investigations for resective epilepsy surgery, including MEG source imaging (MSI). We sought to determine the feasibility and accuracy of MSI in the setting of active thalamic DBS. Simultaneous EEG/MEG was obtained in a patient using an Elekta 306-channel MEG system, with high-frequency (100 Hz) DBS of the thalamic anterior nuclei cycling between on and off states. Magnetic arti

SUBMITTER: Wennberg R 

PROVIDER: S-EPMC5939388 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature