Ontology highlight
ABSTRACT:
SUBMITTER: Graham B
PROVIDER: S-EPMC5940321 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20180419 17
Antifreeze glycoproteins (AFGPs) from polar fish are the most potent ice recrystallization (growth) inhibitors known, and synthetic mimics are required for low-temperature applications such as cell cryopreservation. Here we introduce facially amphipathic glycopolymers that mimic the three-dimensional structure of AFGPs. Glycopolymers featuring segregated hydrophilic and hydrophobic faces were prepared by ring-opening metathesis polymerization, and their rigid conformation was confirmed by small- ...[more]