Ontology highlight
ABSTRACT:
SUBMITTER: Zou J
PROVIDER: S-EPMC5941821 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Evidence-based complementary and alternative medicine : eCAM 20180424
Danshen <i>(Salvia miltiorrhiza)</i> is a well-known herb in Traditional Chinese Medicine (TCM) for treating cardiovascular diseases, but the underlying mechanism remains to be fully elucidated. Here, we showed that Danshen and its active ingredient rosmarinic acid exhibited antiplatelet effects through the inhibition of ERp57, a member of protein disulfide isomerase (PDI) with potential roles in platelet aggregation. Danshen extract (DSE) exhibited potent inhibitory effects on the platelet aggr ...[more]