Dataset Information

Characteristics of young children with developmental delays and their trends over 14 years in Taiwan: a population-based nationwide study.

ABSTRACT: OBJECTIVES:To describe the epidemiological characteristics of developmental delays (DD) at the national level and assess the changes over time. DESIGN:We calculated the incidence rates of DD from 2003 to 2016 and assessed the trends over time. SETTING:As dictated by law, local governments in Taiwan are required to register children with DD and provide services. The central government has constructed a national registry with the data from local centres. We analysed the national registry data. PARTICIPANTS:We included children who were under 6 years old, and this population ranged from 1 164 150 to 1 577 443 per year during the study period. All registered cases were certified through a process set forth by law. PRIMARY AND SECONDARY OUTCOME MEASURES:We calculated annual incidence rates by age, sex and geographical area, and assessed trends over the study period. RESULTS:The incidence of DD in children under 6 years old displayed an increasing trend over the study period, ranging from 7.0 to 16.3 per 1000 person-years. Boys had higher incidence throughout all 14 years, and the boy-to-girl rate ratios had an increasing trend over time with some fluctuations, ranging from 1.84 (95% CI 1.77 to 1.92) to 1.99 (95% CI 1.93 to 2.06). In addition, rural areas had higher incidence rates, and the rural to urban rate ratios ranged from 0.98 (95% CI 0.94 to 1.03) to 2.00 (95% CI 1.94 to 2.06) without apparent time trends. Girls had a higher proportion of early reporting (<3?years) throughout all years, but the differences in the proportion of early reporting between rural and urban areas were not consistent. CONCLUSIONS:Male sex appeared to be a risk factor for DD, which is unlikely to be due to more attention received by boys because girls had a higher proportion of early reporting. We also found that children lived in rural areas appeared to have a higher risk of having DD.

SUBMITTER: Lai DC

PROVIDER: S-EPMC5942477 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Characteristics of young children with developmental delays and their trends over 14 years in Taiwan: a population-based nationwide study.

Lai Der-Chung DC Tseng Yen-Cheng YC Guo How-Ran HR

BMJ open 20180508 5

<h4>Objectives</h4>To describe the epidemiological characteristics of developmental delays (DD) at the national level and assess the changes over time.<h4>Design</h4>We calculated the incidence rates of DD from 2003 to 2016 and assessed the trends over time.<h4>Setting</h4>As dictated by law, local governments in Taiwan are required to register children with DD and provide services. The central government has constructed a national registry with the data from local centres. We analysed the natio ...[more]

PMID: 29739783

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Project description:Background We describe calendar time trends of patients with simple congenital heart disease. Methods and Results Using the nationwide Danish registries, we identified individuals diagnosed with isolated ventricular septal defect, atrial septal defect, patent ductus arteriosus, or pulmonary stenosis during 1977 to 2015, who were alive at 5 years of age. We reported incidence per 1 000 000 person-years with 95% CIs, 1-year invasive cardiac procedure probability and age at time of diagnosis stratified by diagnosis age (children ≤18 years, adults >18 years), and 1-year all-cause mortality stratified by diagnosis age groups (5-30, 30-60, 60+ years). We identified 15 900 individuals with simple congenital heart disease (ventricular septal defect, 35.2%; atrial septal defect, 35.0%; patent ductus arteriosus, 25.2%; pulmonary stenosis, 4.6%), of which 75.7% were children. From 1977 to 1986 and 2007 to 2015, the incidence rates increased for atrial septal defect in adults (8.8 [95% CI, 7.1-10.5] to 31.8 [95% CI, 29.2-34.5]) and in children (26.6 [95% CI, 20.9-32.3] to 150.8 [95% CI, 126.5-175.0]). An increase was only observed in children for ventricular septal defect (72.1 [95% CI, 60.3-83.9] to 115.4 [95% CI, 109.1-121.6]), patent ductus arteriosus (49.2 [95% CI, 39.8-58.5] to 102.2 [95% CI, 86.7-117.6]) and pulmonary stenosis (5.7 [95% CI, 3.0-8.3] to 21.5 [95% CI, 17.2-25.7]) while the incidence rates remained unchanged for adults. From 1977-1986 to 2007-2015, 1-year mortality decreased for all age groups (>60 years, 30.1%-9.6%; 30-60 years, 9.5%-1.0%; 5-30 years, 1.9%-0.0%), and 1-year procedure probability decreased for children (13.8%-6.6%) but increased for adults (13.3%-29.6%) were observed. Conclusions Increasing incidence and treatment and decreasing mortality among individuals with simple congenital heart disease point toward an aging and growing population. Broader screening methods for asymptomatic congenital heart disease are needed to initiate timely treatment and follow-up.

Dataset Information

Characteristics of young children with developmental delays and their trends over 14 years in Taiwan: a population-based nationwide study.

Publications

Characteristics of young children with developmental delays and their trends over 14 years in Taiwan: a population-based nationwide study.

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