Ontology highlight
ABSTRACT:
SUBMITTER: Mielle J
PROVIDER: S-EPMC5943500 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Mielle Julie J Audo Rachel R Hahne Michael M Macia Laurence L Combe Bernard B Morel Jacques J Daien Claire C
Frontiers in immunology 20180503
Despite growing evidence highlighting the relevance of increasing IL-10-producing B cells (B10<sup>+</sup>cells) in autoimmune diseases, their functions in patients are still unknown. The aim of this study was to evaluate the functions of CpG-induced B10<sup>+</sup> cells isolated from healthy controls (HC) and rheumatoid arthritis (RA) patients, on naïve T cell differentiation. We demonstrated that CpG-induced B10<sup>+</sup> cells from HC drove naïve T cell differentiation toward regulatory T ...[more]