Delayed and progressive damages to juvenile mice after moderate traumatic brain injury.
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ABSTRACT:
SUBMITTER: Zhao S
PROVIDER: S-EPMC5943589 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
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Delayed and progressive damages to juvenile mice after moderate traumatic brain injury.
Zhao Shu S Wang Xiaoting X Gao Xiang X Chen Jinhui J
Scientific reports 20180509 1
Symptoms are commonly more severe in pediatric traumatic brain injury (TBI) patients than in young adult TBI patients. To understand the mechanism, juvenile mice received a controlled cortical impact (CCI) injury at moderate level. Tissue lesion and cell death were measured and compared to our previous reports on brain injury in the young adult mice that received same level of impact using same injury device. Tissue lesion and cell death in the cortex was much less in the juvenile mouse brain in ...[more]
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