Evidence supports blind screening for internal malignancy in dermatomyositis: Data from 2 large US dermatology cohorts.

ABSTRACT: The association between dermatomyositis and internal malignancy is well established, but there is little consensus about the methods of cancer screening that should be utilized.We wished to analyze the prevalence and yield of selected cancer screening modalities in patients with dermatomyositis.We performed a retrospective analysis of 2 large US dermatomyositis cohorts comprising 400 patients.We measured the frequency of selected screening tests used to search for malignancy. Patients with a biopsy-confirmed malignancy were identified. Prespecified clinical and laboratory factors were tested for association with malignancy. For each malignancy we identified the screening test(s) that led to diagnosis and classified these tests as either blind (not guided by suspicious sign/symptom) or trig

SUBMITTER: Leatham H 

PROVIDER: S-EPMC5943873 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature