Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC5944199 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Liu Xinnong X Zhu Qingtian Q Zhang Min M Yin Tao T Xu Rong R Xiao Weiming W Wu Jian J Deng Bin B Gao Xuefeng X Gong Weijuan W Lu Guotao G Ding Yanbing Y
Oxidative medicine and cellular longevity 20180426
Oxidative stress plays a crucial role in the pathogenesis of acute pancreatitis (AP). Isoliquiritigenin (ISL) is a flavonoid monomer with confirmed antioxidant activity. However, the specific effects of ISL on AP have not been determined. In this study, we aimed to investigate the protective effect of ISL on AP using two mouse models. In the caerulein-induced mild acute pancreatitis (MAP) model, dynamic changes in oxidative stress injury of the pancreatic tissue were observed after AP onset. We ...[more]