Ontology highlight
ABSTRACT: Background
The endometrial carcinoma (EC) is the most frequently occurring female genital cancer. The authors performed this network meta-analysis to compare operative time and the incidence of bowel injury and wound infection of 3 operative approaches (laparoscopy, laparotomy, and laparoscopic-assisted vaginal hysterectomy [LAVH]) in the treatment of EC.Methods
The Cochrane Library, PubMed, and Embase databases were searched. Randomized controlled trials (RCTs) for EC from the day of databases establishment to February 2017 were included. Direct and indirect evidences were combined to calculate the combined weighted mean difference (WMD) or odd ratio values and the surface under the cumulative ranking curve (SUCRA) value of 3 operative approaches in the treatment of EC.Results
A total of 9 qualified RCTs were included into the study. The results showed that laparotomy had a shorter-operative time than LAVH (WMD?=?-40.36, 95% confidence interval?=?-75.03 to -2.57). However, there was no significant difference in the incidence of bowel injury and wound infection among 3 operative approaches. Besides, the SUCRA values indicated that laparotomy had the shortest operative time but the incidence of bowel injury and wound infection was relatively higher.Conclusion
The results from this study indicate that laparotomy had highest incidence of bowel injury and wound infection but shortest operative time among 3 operative approaches in the treatment of EC.
SUBMITTER: Wang YR
PROVIDER: S-EPMC5944470 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Wang Ya-Ru YR Lu Hui-Fang HF Huo Hui-Can HC Qu Chang-Ping CP Sun Gui-Xia GX Shao Shi-Qing SQ
Medicine 20180401 17
<h4>Background</h4>The endometrial carcinoma (EC) is the most frequently occurring female genital cancer. The authors performed this network meta-analysis to compare operative time and the incidence of bowel injury and wound infection of 3 operative approaches (laparoscopy, laparotomy, and laparoscopic-assisted vaginal hysterectomy [LAVH]) in the treatment of EC.<h4>Methods</h4>The Cochrane Library, PubMed, and Embase databases were searched. Randomized controlled trials (RCTs) for EC from the d ...[more]