Ontology highlight
ABSTRACT:
SUBMITTER: Ghosh M
PROVIDER: S-EPMC5945544 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Ghosh Manosij M Öner Deniz D Duca Radu C RC Bekaert Bram B Vanoirbeek Jeroen A J JAJ Godderis Lode L Hoet Peter H M PHM
Oncotarget 20180417 29
Recent studies have identified carbon nanotube (CNT)-induced epigenetic changes as one of the key players in patho-physiological response. In the present study, we investigated whether CNT exposure is associated with epigenetic changes in human bronchial epithelial cells (16 HBE), <i>in vitro</i>. We focused on global DNA methylation, methylation of <i>LINE-1</i> elements and promoter sequence of twelve functionally important genes (<i>SKI, DNMT1, HDAC4</i>, <i>NPAT, ATM, BCL2L11, MAP3K10, PIK3R ...[more]