Ontology highlight
ABSTRACT:
SUBMITTER: Wilson R
PROVIDER: S-EPMC5945956 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Wilson Robert R Menassa David A DA Davies Alexander J AJ Michael Sophia S Hester Joanna J Kuker Wilhelm W Collins Graham P GP Cossins Judith J Beeson David D Steven Neil N Maddison Paul P Rinaldi Simon S Jacob Saiju S Irani Sarosh R SR
Annals of clinical and translational neurology 20180325 5
Checkpoint inhibitor medications have revolutionized oncology practice, but frequently induce immune-related adverse events. During autoimmune neurology practice over 20 months, we prospectively identified four patients with likely antibody-mediated neurological diseases after checkpoint inhibitors: longitudinally extensive transverse myelitis, Guillain-Barré syndrome, and myasthenia gravis. All patients shared three characteristics: symptoms commenced 4 weeks after drug administration, response ...[more]