Inflammation is a key risk factor for persistent seizures in neurocysticercosis.

ABSTRACT:

Objective

We conducted a retrospective, case-control study of neurocysticercosis patients to ascertain early markers that identify subjects likely to develop treatment-resistant seizures.

Methods

Clinical histories and imaging studies from 38 neurocysticercosis patients who had been followed for 18 months after treatment were evaluated. Both pairwise and multifactorial analyses were conducted to identify factors associated with continued seizures.

Results

Eleven of 38 patients continued to have seizures during the follow-up period. On univariate analysis, the number of neurocysticercosis lesions, number of bands on the baseline neurocysticercosis western blot, edema volumes on follow-up MRI scans, edema volume changes between baseline and follow-up images, and proport

SUBMITTER: Herrick JA 

PROVIDER: S-EPMC5945963 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature