Ontology highlight
ABSTRACT:
SUBMITTER: Guimaraes MA
PROVIDER: S-EPMC5947907 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Guimarães Maria A MA de Oliveira Rosimeire N RN de Almeida Rebeca L RL Mafud Ana C AC Sarkis Ana L V ALV Ganassin Rayane R da Silva Marcos P MP Roquini Daniel B DB Veras Leiz M LM Sawada Tânia C H TCH Ropke Cristina D CD Muehlmann Luis A LA Joanitti Graziella A GA Kuckelhaus Selma A S SAS Allegretti Silmara M SM Mascarenhas Yvonne P YP de Moraes Josué J Leite José R S A JRSA Leite José R S A JRSA
PloS one 20180511 5
Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this parasite that infect humans, S. mansoni is the most common. Pharmacological treatment is limited to the use of a single drug, praziquantel (PZQ), despite reports of parasite resistance and low efficacy. It is therefore necessary to investigate new potential schistosomicidal compounds. In this study, we tested the efficacy of epiisopilosine ...[more]