Dorsomedial Prefrontal Activity to Sadness Predicts Later Emotion Suppression and Depression Severity in Adolescent Girls.
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ABSTRACT:
SUBMITTER: Vilgis V
PROVIDER: S-EPMC5948133 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
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Dorsomedial Prefrontal Activity to Sadness Predicts Later Emotion Suppression and Depression Severity in Adolescent Girls.
Vilgis Veronika V Gelardi Kristina L KL Helm Jonathan L JL Forbes Erika E EE Hipwell Alison E AE Keenan Kate K Guyer Amanda E AE
Child development 20180130 3
The present study used cross-lagged panel analyses to test longitudinal associations among emotion regulation, prefrontal cortex (PFC) function, and depression severity in adolescent girls. The ventromedial and dorsomedial PFC (vmPFC and dmPFC) were regions of interest given their roles in depression pathophysiology, self-referential processing, and emotion regulation. At ages 16 and 17, seventy-eight girls completed a neuroimaging scan to assess changes in vmPFC and dmPFC activation to sad face ...[more]
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