Ontology highlight
ABSTRACT:
SUBMITTER: Salehi A
PROVIDER: S-EPMC5951019 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Salehi Arjang A Jullienne Amandine A Baghchechi Mohsen M Hamer Mary M Walsworth Mark M Donovan Virginia V Tang Jiping J Zhang John H JH Pearce William J WJ Obenaus Andre A
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20171121 2
Recent data suggest that repairing the cerebral vasculature after traumatic brain injury (TBI) may help to improve functional recovery. The Wnt/β-catenin signaling pathway promotes blood vessel formation during vascular development, but its role in vascular repair after TBI remains elusive. In this study, we examined how the cerebral vasculature responds to TBI and the role of Wnt/β-catenin signaling in vascular repair. We induced a moderate controlled cortical impact in adult mice and performed ...[more]