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Control of Mesh Size and Modulus by Kinetically Dependent Cross-Linking in Hydrogels.


ABSTRACT: Kinetically controlled cross-linking processes produce mechanically distinguishable hydrogels using identical precursor chemistry. The oxime ligation demonstrates tunable reaction kinetics with pH and buffer strength, which induce changes in the structural features of hydrogels and determine their mechanical properties. Small-angle neutron scattering and swelling studies provide an insight into how structural properties correlate with mechanical properties for this hydrogel system.

SUBMITTER: Zander ZK 

PROVIDER: S-EPMC5951290 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Control of Mesh Size and Modulus by Kinetically Dependent Cross-Linking in Hydrogels.

Zander Zachary K ZK   Hua Geng G   Wiener Clinton G CG   Vogt Bryan D BD   Becker Matthew L ML  

Advanced materials (Deerfield Beach, Fla.) 20150831 40


Kinetically controlled cross-linking processes produce mechanically distinguishable hydrogels using identical precursor chemistry. The oxime ligation demonstrates tunable reaction kinetics with pH and buffer strength, which induce changes in the structural features of hydrogels and determine their mechanical properties. Small-angle neutron scattering and swelling studies provide an insight into how structural properties correlate with mechanical properties for this hydrogel system. ...[more]

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