Ontology highlight
ABSTRACT:
SUBMITTER: Vieira ML
PROVIDER: S-EPMC5955187 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Vieira Monica L ML Teixeira Aline F AF Pidde Giselle G Ching Ana T C ATC Tambourgi Denise V DV Nascimento Ana Lucia T O ALTO Herwald Heiko H
Virulence 20180101 1
Leptospirosis is a widespread zoonotic and neglected infectious disease of human and veterinary concern that is caused by pathogenic Leptospira species. After entrance in the host, pathogenic leptospires evade the host natural defense mechanisms in order to propagate and disseminate to multiple organs. Myeloperoxidase is an enzyme stored in neutrophils azurophilic granules, and is released upon neutrophil activation to produce mainly hypochlorous acid, a strong oxidant and potent antimicrobial a ...[more]