Ontology highlight
ABSTRACT:
SUBMITTER: Hadad N
PROVIDER: S-EPMC5955819 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Neurobiology of aging 20180316
Brain aging is marked by cognitive decline and susceptibility to neurodegeneration. Calorie restriction (CR) increases neurogenesis, improves memory function, and protects from age-associated neurological disorders. Epigenetic mechanisms, including DNA methylation, are vital to normal central nervous system cellular and memory functions and are dysregulated with aging. The beneficial effects of CR have been proposed to work through epigenetic processes, but this is largely unexplored. We therefo ...[more]