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Adipose Y5R mRNA is higher in obese than non-obese humans and is correlated with obesity parameters.


ABSTRACT: Neuropeptide Y is mainly expressed in the central nervous system to regulate food intake via its receptors, Y receptors, and in various peripheral tissues including adipose tissue. The objectives of this study were to compare Y5R mRNA and adipocyte parameters consisting of area, width, height, and perimeter either between obese and non-obese subjects or between subcutaneous and visceral fat as well as to compare between NPY, Y1R, Y2R, and Y5R mRNA expressions in subcutaneous and visceral adipose tissues. In subcutaneous and visceral adipose tissues, Y5R was greater in obese than in non-obese humans (both P?

SUBMITTER: Chatree S 

PROVIDER: S-EPMC5956667 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Adipose Y5R mRNA is higher in obese than non-obese humans and is correlated with obesity parameters.

Chatree Saimai S   Sitticharoon Chantacha C   Maikaew Pailin P   Uawithya Panapat P   Chearskul Supornpim S  

Experimental biology and medicine (Maywood, N.J.) 20180501 9


Neuropeptide Y is mainly expressed in the central nervous system to regulate food intake via its receptors, Y receptors, and in various peripheral tissues including adipose tissue. The objectives of this study were to compare Y5R mRNA and adipocyte parameters consisting of area, width, height, and perimeter either between obese and non-obese subjects or between subcutaneous and visceral fat as well as to compare between NPY, Y1R, Y2R, and Y5R mRNA expressions in subcutaneous and visceral adipose  ...[more]

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