Ontology highlight
ABSTRACT:
SUBMITTER: Trasnea PI
PROVIDER: S-EPMC5959785 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Trasnea Petru-Iulian PI Andrei Andreea A Marckmann Dorian D Utz Marcel M Khalfaoui-Hassani Bahia B Selamoglu Nur N Daldal Fevzi F Koch Hans-Georg HG
ACS chemical biology 20180409 5
PccA and SenC are periplasmic copper chaperones required for the biogenesis of cbb<sub>3</sub>-type cytochrome c oxidase ( cbb<sub>3</sub>-Cox) in Rhodobacter capsulatus at physiological Cu concentrations. However, both proteins are dispensable for cbb<sub>3</sub>-Cox assembly when the external Cu concentration is high. PccA and SenC bind Cu using Met and His residues and Cys and His residues as ligands, respectively, and both proteins form a complex during cbb<sub>3</sub>-Cox biogenesis. SenC a ...[more]