ZNF804A Variation May Affect Hippocampal-Prefrontal Resting-State Functional Connectivity in Schizophrenic and Healthy Individuals.
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SUBMITTER: Zhang Y
PROVIDER: S-EPMC5960457 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
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ZNF804A Variation May Affect Hippocampal-Prefrontal Resting-State Functional Connectivity in Schizophrenic and Healthy Individuals.
Zhang Yuyanan Y Yan Hao H Liao Jinmin J Yu Hao H Jiang Sisi S Liu Qi Q Zhang Dai D Yue Weihua W
Neuroscience bulletin 20180402 3
The ZNF804A variant rs1344706 has consistently been associated with schizophrenia and plays a role in hippocampal-prefrontal functional connectivity during working memory. Whether the effect exists in the resting state and in patients with schizophrenia remains unclear. In this study, we investigated the ZNF804A polymorphism at rs1344706 in 92 schizophrenic patients and 99 healthy controls of Han Chinese descent, and used resting-state functional magnetic resonance imaging to explore the functio ...[more]
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