Ontology highlight
ABSTRACT:
SUBMITTER: Shin Y
PROVIDER: S-EPMC5963526 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Shin Younghwa Y Moiseyev Gennadiy G Petrukhin Konstantin K Cioffi Christopher L CL Muthuraman Parthasarathy P Takahashi Yusuke Y Ma Jian-Xing JX
Biochimica et biophysica acta. Molecular basis of disease 20180421 7
The retinoid visual cycle is an ocular retinoid metabolism specifically dedicated to support vertebrate vision. The visual cycle serves not only to generate light-sensitive visual chromophore 11-cis-retinal, but also to clear toxic byproducts of normal visual cycle (i.e. all-trans-retinal and its condensation products) from the retina, ensuring both the visual function and the retinal health. Unfortunately, various conditions including genetic predisposition, environment and aging may attribute ...[more]