Ontology highlight
ABSTRACT:
SUBMITTER: Yang TT
PROVIDER: S-EPMC5964178 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Yang T Tony TT Chong Weng Man WM Wang Won-Jing WJ Mazo Gregory G Tanos Barbara B Chen Zhengmin Z Tran Thi Minh Nguyet TMN Chen Yi-De YD Weng Rueyhung Roc RR Huang Chia-En CE Jane Wann-Neng WN Tsou Meng-Fu Bryan MB Liao Jung-Chi JC
Nature communications 20180522 1
Distal appendages (DAPs) are nanoscale, pinwheel-like structures protruding from the distal end of the centriole that mediate membrane docking during ciliogenesis, marking the cilia base around the ciliary gate. Here we determine a super-resolved multiplex of 16 centriole-distal-end components. Surprisingly, rather than pinwheels, intact DAPs exhibit a cone-shaped architecture with components filling the space between each pinwheel blade, a new structural element we term the distal appendage mat ...[more]