An epigenetic classifier for early stage lung cancer.
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ABSTRACT:
SUBMITTER: Su Y
PROVIDER: S-EPMC5964676 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
An epigenetic classifier for early stage lung cancer.
Su Yun Y Fang Hong Bin HB Jiang Feng F
Clinical epigenetics 20180522
<h4>Background</h4>Methylated genes detected in sputum are promise biomarkers for lung cancer. Yet the current PCR technologies for quantification of DNA methylation and diagnostic value of the sputum biomarkers are not sufficient to be used for lung cancer early detection. The emerging droplet digital PCR (ddPCR) is a straightforward means for precise, direct, and absolute quantification of nucleic acids. Here, we investigate whether ddPCR can sensitively and robustly quantify DNA methylation i ...[more]
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