Ontology highlight
ABSTRACT:
SUBMITTER: ICECaP Working Group
PROVIDER: S-EPMC5964738 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Sweeney Christopher C Nakabayashi Mari M Regan Meredith M Xie Wanling W Hayes Julia J Keating Nancy N Li Suhui S Philipson Tomas T Buyse Marc M Halabi Susan S Kantoff Philip P Sartor A Oliver AO Soule Howard H Mahal Brandon B
Journal of the National Cancer Institute 20150925 12
New systemic therapies have prolonged the lives of men with metastatic castration-resistant prostate cancer (mCRPC). Use of these therapies in the adjuvant setting when the disease may be micrometastatic and potentially more sensitive to therapies may decrease mortality from prostate cancer. However, the conduct of adjuvant prostate cancer clinical trials is hampered by taking longer than a decade to reach the meaningful endpoint of overall survival (OS) and the fact that many men never die from ...[more]