Ontology highlight
ABSTRACT:
SUBMITTER: Pai J
PROVIDER: S-EPMC5968531 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Pai Jaeyoung J Hyun Ji Young JY Jeong Jieun J Loh Sohee S Cho Eun-Hee EH Kang Young-Sun YS Shin Injae I
Chemical science 20160105 3
Carbohydrate microarrays have become robust and powerful tools for the rapid analysis of glycan-associated binding events. However, this microarray technology has rarely been applied in studies of glycan-mediated cellular responses. Herein we describe a carbohydrate microarray-based approach for the rapid screening of biologically active glycans that stimulate the production of reactive oxygen species (ROS) through binding to the cell-surface lectin. We employed a microarray assay and a fluoresc ...[more]